Hello. I would like to model a cell by its cytoplasm and its nucleus. I have already tried to model each component and their interactions with internal contact and connectivity but when I tried to simulate it, I had my nucleus fragmented inside the cytoplasm, or gone out of the cytoplasm. Do you have any ideas to prevent these from happening? Thank you.
Could you post your simulation here? Cell fragmentation could be prevented by imposing surface and volume constraints. In any case if you could share your code we could try helping you out otherwise it is hard to give you specific advice without seeing all the parameters you have in your model